The easiest trick is to override /etc/localtime:

# ln -sf /usr/share/zoneinfo/Europe/Prague /etc/localtime

According to the BIOS clocks and BIOS-UTC setting of the OS it is usually good idea to correct time:

# date +%T -s "22:30"

It's also quite good idea to start NTP daemon:

# service ntpd restart
# chkconfig ntpd on

For Fedora/RHEL systems you should also update sysconfig file to make this permanent:

# echo 'ZONE="Europe/Prague"' > /etc/sysconfig/clock

This is very important if you run a virtual guest since clocks are not very accurate for them.